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Literature summary for 3.1.1.64 extracted from
- FATP1 inhibits 11-cis retinol formation via interaction with the visual cycle retinoid isomerase RPE65 and LRAT (2010), J. Biol. Chem., 285, 18759-18768.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Sf9 cells and in 29T cells | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| FATP1c | cytosolic C-terminal sequence from the fatty acid transport protein 1 (FATP1or SLC27A1, solute carrier family 27member1), interacts dose-dependently with the native RPE65 and markedly inhibits 11-cis retinol production by acting on the production of all-trans retinyl esters and the isomerase activity of RPE65 | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| retinal pigment epithelium | - |
Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Rpe65 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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