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Literature summary for 3.1.1.59 extracted from

  • Kontogiannatos, D.; Swevers, L.; Maenaka, K.; Park, E.Y.; Iatrou, K.; Kourti, A.
    Functional characterization of a juvenile hormone esterase related gene in the moth Sesamia nonagrioides through RNA interference (2013), PLoS ONE, 8, e73834.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.1.59

Cloned(Commentary)

Cloned (Comment) Organism
cloning of an ecdysteroid sensitiv and juvenile hormone non-susceptible juvenile hormone esterase related gene, expression in Escherichia coli strain HT115 (DE3) Sesamia nonagrioides

Protein Variants

Protein Variants Comment Organism
additional information silencing of the enzyme by RNA interference, i.e. baculovirus-mediated RNAi, no specific phenotype, overview Sesamia nonagrioides

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
juvenile hormone + H2O Sesamia nonagrioides
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Sesamia nonagrioides A8VJM0
-
-

Source Tissue

Source Tissue Comment Organism Textmining
hemolymph
-
 Sesamia nonagrioides
-
larva the enzyme is rhythmically up-regulated close to each molt during the Sesamia nonagrioides larval development Sesamia nonagrioides
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
juvenile hormone + H2O
-
 Sesamia nonagrioides ?
-
 ?

Synonyms

Synonyms Comment Organism
JHE
-
 Sesamia nonagrioides
Juvenile hormone esterase
-
 Sesamia nonagrioides

Expression

Organism Comment Expression
Sesamia nonagrioides the enzyme is rhythmically up-regulated close to each molt during the corn stalk borer's larval development up

General Information

General Information Comment Organism
malfunction silencing of the enzyme affects expression of the other developmental genes without a specific phenotype, e.g. mRNA accumulation of heat shock protein 70, SnHsp70, is increased while the heat shock cognate 70, SnHsc70, and ecdysone receptor, SnEcR, mRNA accumulation is decreased Sesamia nonagrioides
physiological function the enzyme plays a critical role in regulating larval to adult transition in insects and other arthropods. It is following the ecdysteroid titer of Sesamia nonagrioides in contrast to other conventional JHE genes of several insects. The enzyme is implicated in larval-larval molt of Sesamia nonagrioides larvae. The enzyme is implicated in the ecdysteroid instead of the juvenile hormone signalling by interfering with the molting process Sesamia nonagrioides