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Literature summary for 3.1.1.59 extracted from
- Effect of octopamine on the activity of juvenile-hormone esterase in the silkworm Bombyx mori and the red flour beetle Tribolium freemani (1999), Gen. Comp. Endocrinol., 116, 373-381.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| 1-(4-chloro-2-methylphenyl)imidazolidine-2-thione | octopamine agonist, stimulates the pupation and JHE activity of larvae reared under crowded conditions, when topically applied, 0.05 mg | Tribolium freemani |  |
| 2-(4-chloro-2-methylphenylimino)oxazolidine | octopamine agonist, stimulates the pupation and JHE activity of larvae reared under crowded conditions, when topically applied, 0.05 mg | Tribolium freemani | |
| chlordimeform | octopamine agonist, stimulates the pupation and JHE activity of larvae reared under crowded conditions, when topically applied, 0.01 mg | Tribolium freemani | |
| octopamine | 10 mM, activates JHE activity of newly ecdysed pupae | Tribolium freemani | |
| octopamine | exogenous octopamine, 0.1 -10 mM, stimulates JHE activity of final instars at day 2 | Bombyx mori | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| chlorpromazine | octopamine antagonist, reduces JHE activity, when applied in diet at 10-100 ppm | Bombyx mori | |
| gramine | octopamine antagonist, reduces JHE activity, when applied in diet at 10-100 ppm | Bombyx mori | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bombyx mori | - |
hybrid-strain Shogetu-Shunrei | - |
| Bombyx mori Shogetu-Shunrei | - |
hybrid-strain Shogetu-Shunrei | - |
| Tribolium freemani | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| hemolymph | of fourth and fifth instars | Bombyx mori | - |
| larva | JHE activity at various larval and pupal stadia | Tribolium freemani | - |
| larva | JHE activity at various larval and pupal stadia, hemolymph of fourth and fifth instars, whole body of third instar | Bombyx mori | - |
| pupa | JHE activity at various larval and pupal stadia | Bombyx mori | - |
| pupa | JHE activity at various larval and pupal stadia | Tribolium freemani | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
JHE activity at various larval and pupal stadia | Bombyx mori |
| additional information | - |
JHE activity at various larval and pupal stadia | Tribolium freemani |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| juvenile hormone III + H2O | - |
Bombyx mori | juvenile hormone III acid + methanol | - |
? | |
| juvenile hormone III + H2O | - |
Tribolium freemani | juvenile hormone III acid + methanol | - |
? | |
| juvenile hormone III + H2O | - |
Bombyx mori Shogetu-Shunrei | juvenile hormone III acid + methanol | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| JHE | - |
Bombyx mori |
| JHE | - |
Tribolium freemani |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | - |
assay at | Tribolium freemani |
| 35 | - |
assay at | Bombyx mori |
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