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Literature summary for 3.1.1.55 extracted from

  • White, K.N.; Vale, V.L.; Hope, D.B.
    Identification of common forms of salicylate esterases in guinea-pig tissues similar to the microsomal aspirinases of liver (1994), Biochem. Soc. Trans., 22, 220S.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
bis(4-nitrophenyl)hydrogen phosphate i.e. BNPP, organophosphate carboxylesterase inhibitor, enzymes from intestinal and gastric mucosa are inhibited by 80% at 0.1 mM, while the liver enzyme shows only 25% inhibition Cavia porcellus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Cavia porcellus 5829
-
microsome
-
Cavia porcellus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acetyl salicylate + H2O Cavia porcellus i.e. aspirin salicylate + acetate
-
?

Organism

Organism UniProt Comment Textmining
Cavia porcellus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
gastric mucosa cytosol Cavia porcellus
-
intestinal mucosa
-
Cavia porcellus
-
kidney
-
Cavia porcellus
-
liver
-
Cavia porcellus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl salicylate + H2O i.e. aspirin Cavia porcellus salicylate + acetate
-
?
acetylsalicylate + H2O i.e. aspirin Cavia porcellus salicylate + acetate
-
?