Inhibitors | Comment | Organism | Structure |
---|---|---|---|
bis(4-nitrophenyl)hydrogen phosphate | irreversible, complete inhibition | Cavia porcellus | |
bis-4-nitrophenyl phosphate | - |
Cavia porcellus | |
additional information | substrate inhibition increases with increasing chain length of the fatty acid on the ester | Cavia porcellus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.132 | - |
n-Decanoyl salicylate | pH 8.0, 37°C | Cavia porcellus | |
0.201 | - |
n-Octanoyl salicylate | pH 8.0, 37°C | Cavia porcellus | |
0.447 | - |
Acetyl salicylate | pH 8.0, 37°C | Cavia porcellus | |
0.576 | - |
n-Propionyl salicylate | pH 8.0, 37°C | Cavia porcellus | |
0.679 | - |
n-Hexanoyl salicylate | pH 8.0, 37°C | Cavia porcellus | |
0.799 | - |
n-Butyryl salicylate | pH 8.0, 37°C | Cavia porcellus | |
0.983 | - |
n-Pentanoyl salicylate | pH 8.0, 37°C | Cavia porcellus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Cavia porcellus | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
54300 | - |
gel filtration | Cavia porcellus |
57100 | - |
1 * 57100, SDS-PAGE | Cavia porcellus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl salicylate + H2O | Cavia porcellus | i.e. aspirin | salicylate + acetate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Cavia porcellus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partial | Cavia porcellus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Cavia porcellus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Cavia porcellus |
11.31 | - |
partially purified enzyme, substrate acetyl salicylate | Cavia porcellus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl salicylate + H2O | i.e. aspirin | Cavia porcellus | salicylate + acetate | - |
? | |
acetylsalicylate + H2O | i.e. aspirin | Cavia porcellus | salicylate + acetate | - |
? | |
n-butyryl salicylate + H2O | - |
Cavia porcellus | 2-hydroxybenzoate + butyrate | - |
? | |
n-decanoyl salicylate + H2O | - |
Cavia porcellus | 2-hydroxybenzoate + n-decanoate | - |
? | |
n-hexanoyl salicylate + H2O | - |
Cavia porcellus | 2-hydroxybenzoate + n-hexanoate | - |
? | |
n-octanoyl salicylate + H2O | - |
Cavia porcellus | 2-hydroxybenzoate + n-octanoate | - |
? | |
n-pentanoyl salicylate + H2O | - |
Cavia porcellus | 2-hydroxybenzoate + n-pentanoate | - |
? | |
n-propionyl salicylate + H2O | - |
Cavia porcellus | 2-hydroxybenzoate + propionate | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 57100, SDS-PAGE | Cavia porcellus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Cavia porcellus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | 8.5 | - |
Cavia porcellus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
5.5 | 9 | pH 5.5: about 50% of activity maximum, pH 9: about 75% of activity maximum | Cavia porcellus |