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Literature summary for 3.1.1.5 extracted from

  • Coe, J.G.S.; Wilson, C.F.; Sorrell, T.C.; Latouche, N.G.; Wright, L.C.
    Cloning of CnLYSO1, a novel extracellular lysophospholipase of the pathogenic fungus Cryptococcus neoformans (2003), Gene, 316, 67-78.
    View publication on PubMed
Search for more literature for 3.1.1.5

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli and Saccharomyces cerevisiae Cryptococcus neoformans

General Stability

General Stability Organism
unstable upon purification, enzyme activity is lost during storage at 4°C or -70°C Cryptococcus neoformans

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
 Cryptococcus neoformans
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
48000
-
 x * 48000, deduced from nucleotide sequence Cryptococcus neoformans

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2-lysophosphatidylcholine + H2O Cryptococcus neoformans
-
 glycerophosphocholine + a carboxylate
-
 ?

Organism

Organism UniProt Comment Textmining
Cryptococcus neoformans Q8NKD2 var. grubii
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-lysophosphatidylcholine + H2O
-
 Cryptococcus neoformans glycerophosphocholine + a carboxylate
-
 ?
2-lysophosphatidylcholine + H2O enzyme has also lysophospholipase transcylase activity Cryptococcus neoformans glycerophosphocholine + a carboxylate
-
 ?

Subunits

Subunits Comment Organism
? x * 48000, deduced from nucleotide sequence Cryptococcus neoformans
? x * 97000-140000, SDS-PAGE, immunoblot Cryptococcus neoformans

Synonyms

Synonyms Comment Organism
CnLYSO1
-
 Cryptococcus neoformans

pI Value

Organism Comment pI Value Maximum pI Value
Cryptococcus neoformans predicted from nucleotide sequence
-
 6.4