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Literature summary for 3.1.1.47 extracted from
- Lipid mediators and vector infection: Trypanosoma rangeli inhibits Rhodnius prolixus hemocyte phagocytosis by modulation of phospholipase A2 and PAF-acetylhydrolase activities (2008), J. Insect Physiol., 54, 1528-1537.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rhodnius prolixus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| hemocyte | - |
Rhodnius prolixus | - |
| hemolymph | - |
Rhodnius prolixus | - |
| larva | - |
Rhodnius prolixus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 4.5 | - |
Ca2+-dependent PLA2, cell-free hemolymph of Rhodnius prolixus feeding with blood plus dexamethasone | Rhodnius prolixus |
| 6.7 | - |
Ca2+-dependent PLA2, control, cell-free hemolymph of Rhodnius prolixus after regular blood feeding | Rhodnius prolixus |
| 10.7 | - |
Ca2+-dependent PLA2, cell-free hemolymph of Rhodnius prolixus feeding with Trypanosoma rangeli epimastigotes | Rhodnius prolixus |
| 12 | - |
Ca2+-independent PLA2, cell-free hemolymph of Rhodnius prolixus feeding with blood plus dexamethasone | Rhodnius prolixus |
| 14 | - |
Ca2+-independent PLA2, control, cell-free hemolymph of Rhodnius prolixus after regular blood feeding | Rhodnius prolixus |
| 17 | - |
total PLA2, cell-free hemolymph of Rhodnius prolixus feeding with blood plus dexamethasone | Rhodnius prolixus |
| 21 | - |
total PLA2, control, cell-free hemolymph of Rhodnius prolixus after regular blood feeding | Rhodnius prolixus |
| 24 | - |
PAF-AH, control, cell-free hemolymph of Rhodnius prolixus after regular blood feeding | Rhodnius prolixus |
| 32 | - |
Ca2+-independent PLA2, cell-free hemolymph of Rhodnius prolixus feeding with Trypanosoma rangeli epimastigotes | Rhodnius prolixus |
| 34 | - |
PAF-AH, cell-free hemolymph of Rhodnius prolixus feeding with blood plus dexamethasone | Rhodnius prolixus |
| 43 | - |
total PLA2, cell-free hemolymph of Rhodnius prolixus feeding with Trypanosoma rangeli epimastigotes | Rhodnius prolixus |
| 119 | - |
Ca2+-independent PLA2, hemocyte of Rhodnius prolixus feeding with Trypanosoma rangeli epimastigotes | Rhodnius prolixus |
| 140 | - |
Ca2+-independent PLA2, hemocyte of Rhodnius prolixus feeding with blood plus dexamethasone | Rhodnius prolixus |
| 186 | - |
Ca2+-independent PLA2, control, hemocyte of Rhodnius prolixus after regular blood feeding | Rhodnius prolixus |
| 203 | - |
PAF-AH, cell-free hemolymph of Rhodnius prolixus feeding with Trypanosoma rangeli epimastigotes | Rhodnius prolixus |
| 381 | - |
Ca2+-dependent PLA2, hemocyte of Rhodnius prolixus feeding with blood plus dexamethasone | Rhodnius prolixus |
| 427 | - |
Ca2+-dependent PLA2, hemocyte of Rhodnius prolixus feeding with Trypanosoma rangeli epimastigotes | Rhodnius prolixus |
| 529 | - |
total PLA2, hemocyte of Rhodnius prolixus feeding with blood plus dexamethasone | Rhodnius prolixus |
| 570 | - |
total PLA2, hemocyte of Rhodnius prolixus feeding with Trypanosoma rangeli epimastigotes | Rhodnius prolixus |
| 702 | - |
Ca2+-dependent PLA2, control, hemocyte of Rhodnius prolixus after regular blood feeding | Rhodnius prolixus |
| 915 | - |
total PLA2, control, hemocyte of Rhodnius prolixus after regular blood feeding | Rhodnius prolixus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1-palmitoyl-2-[12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-sn-glycero-3-phosphocholine + H2O | substrate activity assay | Rhodnius prolixus | ? | - |
? |  |
| 1-palmitoyl-2-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-sn-glycero-3-phosphocholine + H2O | substrate activity assay | Rhodnius prolixus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PAF-acetylhydrolase | - |
Rhodnius prolixus |
| PAF-AH | - |
Rhodnius prolixus |
| phospholipase A2 | - |
Rhodnius prolixus |
| PLA2 | - |
Rhodnius prolixus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
activity assay | Rhodnius prolixus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | - |
activity assay | Rhodnius prolixus |
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