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Literature summary for 3.1.1.47 extracted from

  • Umemura, K.; Kato, I.; Hirashima, Y.; Ishii, Y.; Inoue, T.; Aoki, J.; Kono, N.; Oya, T.; Hayashi, N.; Hamada, H.; Endo, S.; Oda, M.; Arai, H.; Kinouchi, H.; Hiraga, K.
    Neuroprotective role of transgenic PAF-acetylhydrolase II in mouse models of focal cerebral ischemia (2007), Stroke, 38, 1063-1068.
    View publication on PubMed
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Application

Application Comment Organism
medicine PAF-AH II exerts strong neuroprotective effects against ischemic injury. This results suggest a possibility for clinical use of this enzyme in cerebral ischemia Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
transgenic mice overexpressing human PAF-AH II in neurons are generated. Human PAF-AH II expression is found throughout the central nervous system, especially in neurons of neocortex, hippocampus, and basal ganglia Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens PAF-AH II exerts strong neuroprotective effects against ischemic injury ?
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Organism

Organism UniProt Comment Textmining
Homo sapiens Q99487
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Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information PAF-AH II exerts strong neuroprotective effects against ischemic injury Homo sapiens ?
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 ?