Literature summary for 3.1.1.47 extracted from

Grypioti, A.D.; Mykoniatis, M.; Demopoulos, C.A.; Kostopanagiotou, G.
Recombinant platelet-activating factor-acetylhydrolase attenuates paracetamol-induced liver oxidative stress, injury, and regeneration (2007), Digest. Dis. Sci., 52, 192-199.

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Application

Application	Comment	Organism
medicine	the use of PAF inactivator enhances the livers recovery from paracetamol intoxication and attenuates the severity of experimental liver injury, providing important means of improving liver function following paracetamol intoxication	Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Rattus norvegicus	recombinant platelet-activating factor-acetylhydrolase attenuates paracetamol-induced liver oxidative stress, injury, and regeneration	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	O35264 and O35263	lysophospholipase and beta-subunit and gamma-subunit; male Wistar	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	recombinant platelet-activating factor-acetylhydrolase attenuates paracetamol-induced liver oxidative stress, injury, and regeneration	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	recombinant platelet-activating factor-acetylhydrolase attenuates paracetamol-induced liver oxidative stress, injury, and regeneration	Rattus norvegicus	?	-	?

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Release 2023.1 (January 2023)