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Literature summary for 3.1.1.4 extracted from

  • De-Paula, V.J.; Schaeffer, E.L.; Talib, L.L.; Gattaz, W.F.; Forlenza, O.V.
    Inhibition of phospholipase A2 increases Tau phosphorylation at Ser214 in embryonic rat hippocampal neurons (2010), Prostaglandins Leukot. Essent. Fatty Acids, 82, 57-60.
    View publication on PubMed
Search for more literature for 3.1.1.4

Inhibitors

Inhibitors Comment Organism Structure
methyl-arachidonylfluorophosphonate irreversible inhibitor of cPLA2 and iPLA2. Ser214 site in microtubule-associated protein Tau is hyperphosphorylated upon inhibitor treatment Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 Wistar rats
-

Source Tissue

Source Tissue Comment Organism Textmining
embryo
-
 Rattus norvegicus
-
hippocampus
-
 Rattus norvegicus
-
neuron
-
 Rattus norvegicus
-

Synonyms

Synonyms Comment Organism
calcium-d-independent cytosolic PLA2
-
 Rattus norvegicus
calcium-dependent cytosolic PLA2
-
 Rattus norvegicus
cPLA2
-
 Rattus norvegicus
iPLA2
-
 Rattus norvegicus

General Information

General Information Comment Organism
physiological function PLA2 signaling pathways indirectly influence the phosphorylation state of Tau Rattus norvegicus