Organism | UniProt | Comment | Textmining |
---|---|---|---|
Naja mossambica | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
venom | - |
Naja mossambica | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1,2-dipalmitoyl-phosphatidylcholine + H2O | hydrolyzes the sn-2 position of a phospholipid liberating a fatty acid and a lysolipid | Naja mossambica | 1-palmitoyl-glycerophosphorylcholine + palmitic acid | - |
? |
Synonyms | Comment | Organism |
---|---|---|
phospholipase A2 | - |
Naja mossambica |
PLA2 | - |
Naja mossambica |
General Information | Comment | Organism |
---|---|---|
metabolism | hydrolyzes dipalmitoylphosphatidylcholine monolayers in the presence of a supersaturated calcium oxalate subphase, inducing the rapid and plentiful nucleation of calcium oxalate at the lipid interface. Calcium oxalate crystal growth at a ternary monolayer of dipalmitoylphosphatidylcholine, palmitic acid, and a 22-carbon chain lysophospholipid dramatically increases relative to monolayers of just dipalmitoylphosphatidylcholine | Naja mossambica |
physiological function | possible link between increased phospholipase activity, which is associated with hyperoxaluria, and calcium oxalate precipitation | Naja mossambica |