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Literature summary for 3.1.1.4 extracted from

  • Souza, A.D.; Rodrigues-Filho, E.; Souza, A.Q.; Pereira, J.O.; Calgarotto, A.K.; Maso, V.; Marangoni, S.; Da Silva, S.L.
    Koninginins, phospholipase A2 inhibitors from endophytic fungus Trichoderma koningii (2008), Toxicon, 51, 240-250.
    View publication on PubMed
Search for more literature for 3.1.1.4

Inhibitors

Inhibitors Comment Organism Structure
koninginin E KonE, isolated from Trichoderma koningii, inhibits edema-inducing, myotoxic and enzymatic activities of PLA2. Action mode in comparison to vitmain E inhibition Bothrops jararacussu
koninginin E KonE, isolated from Trichoderma koningii, inhibits edema-inducing, myotoxic and enzymatic activities of PLA2 Homo sapiens
koninginin F KonF, isolated from Trichoderma koningii, inhibits edema-inducing, myotoxic and enzymatic activities of PLA2. Action mode in comparison to vitmain E inhibition Bothrops jararacussu
koninginin F KonF, isolated from Trichoderma koningii, inhibits edema-inducing, myotoxic and enzymatic activities of PLA2 Homo sapiens
additional information no inhibition by koninginin A, KonA, isolated from Trichoderma koningii Bothrops jararacussu
additional information no inhibition by koninginin A, KonA, isolated from Trichoderma koningii Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
 Bothrops jararacussu
-
-
extracellular the group IIA enzyme is secreted Homo sapiens
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+
-
 Homo sapiens
Ca2+
-
 Bothrops jararacussu

Organism

Organism UniProt Comment Textmining
Bothrops jararacussu
-
-
-
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
venom
-
 Bothrops jararacussu
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-hexadecanoyl-2-(10-(1-pyrene)decanoyl)-sn-glycero-3-phosphoglycerol + H2O
-
 Homo sapiens 1-hexadecanoyl-sn-glycero-3-phosphoglycerol + 10-(1-pyrene)decanoic acid
-
 ?
1-hexadecanoyl-2-(10-(1-pyrene)decanoyl)-sn-glycero-3-phosphoglycerol + H2O
-
 Bothrops jararacussu 1-hexadecanoyl-sn-glycero-3-phosphoglycerol + 10-(1-pyrene)decanoic acid
-
 ?
4-nitro-3-octanoyloxy-benzoic acid + H2O
-
 Homo sapiens ?
-
 ?
4-nitro-3-octanoyloxy-benzoic acid + H2O
-
 Bothrops jararacussu ?
-
 ?

Synonyms

Synonyms Comment Organism
More a group IIB isozyme Bothrops jararacussu
PLA2
-
 Bothrops jararacussu
PLA2 a group IIA isozyme Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens
37
-
 assay at Bothrops jararacussu

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
 assay at Homo sapiens
8
-
 assay at Bothrops jararacussu