Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | - |
Vipera ammodytes | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | required | Vipera ammodytes |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Vipera ammodytes | the snake phospholipase A2 neurotoxins enter nerve terminals, bind specifically to mitochondria, and open their transition pores, overview. The action of SPANs is very specific for the presynaptic nerve terminals in vivo | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Vipera ammodytes | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
additional information | intracellular localization of SPANs in different primary neuronal cultures from rats and mice after application, fluorescent neurotoxin is not homogeneously distributed in the cytosol but rather localized to elongated, spaghetti-like structures that are clearly reminiscent of mitochondria, overview | Vipera ammodytes | - |
venom | - |
Vipera ammodytes | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the snake phospholipase A2 neurotoxins enter nerve terminals, bind specifically to mitochondria, and open their transition pores, overview. The action of SPANs is very specific for the presynaptic nerve terminals in vivo | Vipera ammodytes | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ammodytoxin A | - |
Vipera ammodytes |
phospholipase A2 neurotoxin | - |
Vipera ammodytes |
PLA2 neurotoxin | - |
Vipera ammodytes |
snake presynoptic phospholipase A2 neurotoxin | - |
Vipera ammodytes |
SPAN | - |
Vipera ammodytes |