Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Cdcas F3 | a crotapotin | Bothrops jararacussu | |
Cdcas F4 | a crotapotin | Bothrops jararacussu | |
Cdcoll F3 | a crotapotin | Bothrops jararacussu | |
Cdcoll F4 | a crotapotin | Bothrops jararacussu | |
Cdt F7 | a crotapotin | Bothrops jararacussu | |
Cu2+ | at 10 mM, diminishes activation in presence of 1 mM Ca2+, slight activation in absence of Ca2+ | Bothrops jararacussu | |
Mg2+ | at 10 mM, diminishes activation in presence of 1 mM Ca2+, poor activation in absence of Ca2+ | Bothrops jararacussu | |
Zn2+ | at 10 mM, diminishes activation in presence of 1 mM Ca2+, no activation in absence of Ca2+ | Bothrops jararacussu |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | - |
Bothrops jararacussu | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | required at 10 mM for full activity | Bothrops jararacussu | |
Cu2+ | at 10 mM, diminishes activation in presence of 1 mM Ca2+, slight activation in absence of Ca2+ | Bothrops jararacussu | |
Mg2+ | at 10 mM, diminishes activation in presence of 1 mM Ca2+, poor activation in absence of Ca2+ | Bothrops jararacussu | |
Mn2+ | activates at 10 mM in presence of 1 mM Ca2+ | Bothrops jararacussu |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Bothrops jararacussu | the enzyme is a component of the venom and causes cytotoxic lesions in murine skeletal muscle C2C12 myoblasts and myotubes, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bothrops jararacussu | - |
isozyme Bj-V | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
venom | - |
Bothrops jararacussu | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme is a component of the venom and causes cytotoxic lesions in murine skeletal muscle C2C12 myoblasts and myotubes, overview | Bothrops jararacussu | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 14039.5, isozyme Bj-V, mass spectrometry and native PAGE | Bothrops jararacussu |
Synonyms | Comment | Organism |
---|---|---|
Bj-V | - |
Bothrops jararacussu |
PLA2 | - |
Bothrops jararacussu |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
35 | 40 | - |
Bothrops jararacussu |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.4 | - |
- |
Bothrops jararacussu |