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Literature summary for 3.1.1.4 extracted from

  • Saliba, A.M.; Nascimento, D.O.; Silva, M.C.A.; Assis, M.C.; Gayer, C.R.M.; Raymond, B.; Coelho, M.G.P.; Marques, E.A.; Touqui, L.; Albano, R.M.; Lopes, U.G.; Paiva, D.D.; Bozza, P.T.; Plotkowski, M.C.
    Eicosanoid-mediated proinflammatory activity of Pseudomonas aeruginosa ExoU (2005), Cell. Microbiol., 7, 1811-1822.
    View publication on PubMed
Search for more literature for 3.1.1.4

Inhibitors

Inhibitors Comment Organism Structure
DNA containing thymine glycol i.e. MAFP, a specific PLA2 inhibitor Pseudomonas aeruginosa
prostaglandin PGE2
-
 Pseudomonas aeruginosa
prostaglandin PGI2
-
 Pseudomonas aeruginosa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Pseudomonas aeruginosa infection by ExoU-producing Pseudomonas aeruginosa induces a rapid release of arachidonic acid as well as a significant release of prostaglandins PGE2 and PGI2 from human endothelial cells of the HMEC-1 line, overview, ExoU may contribute to Pseudomonas aeruginosa pathogenesis by inducing an eicosanoid-mediated inflammatory response of host organisms, overview ?
-
 ?
additional information Pseudomonas aeruginosa PA103 infection by ExoU-producing Pseudomonas aeruginosa induces a rapid release of arachidonic acid as well as a significant release of prostaglandins PGE2 and PGI2 from human endothelial cells of the HMEC-1 line, overview, ExoU may contribute to Pseudomonas aeruginosa pathogenesis by inducing an eicosanoid-mediated inflammatory response of host organisms, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Pseudomonas aeruginosa
-
-
-
Pseudomonas aeruginosa PA103
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Pseudomonas aeruginosa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information infection by ExoU-producing Pseudomonas aeruginosa induces a rapid release of arachidonic acid as well as a significant release of prostaglandins PGE2 and PGI2 from human endothelial cells of the HMEC-1 line, overview, ExoU may contribute to Pseudomonas aeruginosa pathogenesis by inducing an eicosanoid-mediated inflammatory response of host organisms, overview Pseudomonas aeruginosa ?
-
 ?
additional information infection by ExoU-producing Pseudomonas aeruginosa induces a rapid release of arachidonic acid as well as a significant release of prostaglandins PGE2 and PGI2 from human endothelial cells of the HMEC-1 line, overview, ExoU may contribute to Pseudomonas aeruginosa pathogenesis by inducing an eicosanoid-mediated inflammatory response of host organisms, overview Pseudomonas aeruginosa PA103 ?
-
 ?

Synonyms

Synonyms Comment Organism
cytotoxin ExoU
-
 Pseudomonas aeruginosa