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Literature summary for 3.1.1.4 extracted from

  • Satish, S.; Tejaswini, J.; Krishnakantha, T.P.; Gowda, T.V.
    Purification of a Class B1 platelet aggregation inhibitor phospholipase A2 from Indian cobra (Naja Naja) venom (2004), Biochimie, 86, 203-210.
    View publication on PubMed
Search for more literature for 3.1.1.4

Inhibitors

Inhibitors Comment Organism Structure
aristolochic acid partial inhibition of catalytic activity Naja naja
p-bromophenacyl bromide complete loss of both catalytic activity and platelet aggregation inhibitory activity Naja naja

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
13262
-
 x * 13262, MALDI-MS Naja naja

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Naja naja enzyme is a class B1 platelet aggregation inhibitor and inhibits platelet aggregation induced by ADP, collagen and epinephrine ?
-
 ?

Organism

Organism UniProt Comment Textmining
Naja naja
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
venom
-
 Naja naja
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
34
-
 pH 7.5 Naja naja

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme is a class B1 platelet aggregation inhibitor and inhibits platelet aggregation induced by ADP, collagen and epinephrine Naja naja ?
-
 ?
phosphatidylcholine + H2O
-
 Naja naja 1-acylglycerophosphocholine + fatty acid
-
 ?

Subunits

Subunits Comment Organism
? x * 13262, MALDI-MS Naja naja

Synonyms

Synonyms Comment Organism
NND-IV-PLA2
-
 Naja naja