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Literature summary for 3.1.1.4 extracted from
- Phospholipase A2 (phosphatide acylhydrolase, EC 3.1.1.4) from porcine pancreas (1974), Methods Enzymol., 32, 147-154.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1-sn-phosphoglycerides | - |
Sus scrofa |  |
| Ba2+ | competitive inhibition | Sus scrofa | |
| Sr2+ | competitive inhibition | Sus scrofa | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | - |
Sus scrofa | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1,2-diacyl-sn-glycero-3-phosphatide + H2O | Sus scrofa | - |
? | - |
? | |
| phospholipids + H2O | Sus scrofa | - |
? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Sus scrofa | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| column chromatography | Sus scrofa |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| pancreas | - |
Sus scrofa | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 1000 | - |
substrate: egg yolk emulsion | Sus scrofa |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -20°C, lyophilized enzyme, for years | Sus scrofa |
| 4°C, aqueous solution of 1 mg protein per ml, pH 6, more than 90% of enzymes activity remains after 2-3 weeks | Sus scrofa |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1,2-diacyl-sn-glycero-3-phosphatide + H2O | - |
Sus scrofa | 1-acyl-sn-glycero-3-phosphatide + fatty acid | - |
? | |
| 1,2-diacyl-sn-glycero-3-phosphatide + H2O | - |
Sus scrofa | ? | - |
? | |
| 1,2-diacyl-sn-glycero-3-phosphorylcholine + H2O | - |
Sus scrofa | 1-acyl-sn-glycero-3-phosphorylcholine + fatty acid | - |
? | |
| cardiolipin + H2O | - |
Sus scrofa | ? | - |
? | |
| phosphatidic acid + H2O | - |
Sus scrofa | 1-acylglycerophosphate + fatty acid | - |
? | |
| phosphatidylglycerol + H2O | - |
Sus scrofa | 1-acylglycerol + fatty acid | - |
? | |
| phospholipids + H2O | - |
Sus scrofa | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | - |
Sus scrofa |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6 | - |
substrate: water-soluble short-chain lecithin | Sus scrofa |
| 8 | - |
substrate: long-chain neutral lecithin | Sus scrofa |
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Release 2023.1 (January 2023)
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