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Literature summary for 3.1.1.4 extracted from
- Characterization of phospholipase A from pulmonary secretions of patients with alveolar proteinosis (1977), Biochim. Biophys. Acta, 489, 307-317.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| deoxycholate | - |
Homo sapiens |  |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | - |
Homo sapiens | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 75000 | - |
SDS-PAGE | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| phospholipids + H2O | Homo sapiens | - |
? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| ion-exchange chromatography, gel-filtration | Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| lung | pulmonary secretions | Homo sapiens | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 1140 | - |
substrate: egg yolk emulsion | Homo sapiens |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -20°C, lyophilized enzyme, no loss of activity over 3 months | Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1,2-dimyristoyl-sn-phosphatidylcholine + H2O | - |
Homo sapiens | 1-myristoyl-phosphorylcholine + myristic acid | - |
? | |
| 1,2-dipalmitoyl-phosphatidylcholine + H2O | - |
Homo sapiens | 1-palmitoyl-glycerophosphorylcholine + palmitic acid | - |
? | |
| 1,2-dipalmitoyl-phosphatidylethanolamine + H2O | - |
Homo sapiens | 1-palmitoyl-phosphatidylethanolamine + palmitic acid | - |
? | |
| 1-oleoyl-2-palmitoyl-phosphatidylcholine + H2O | - |
Homo sapiens | 1-oleoyl-phosphatidylcholine + palmitic acid | - |
? | |
| 1-palmitoyl-2-oleoylphosphatidylcholine + H2O | - |
Homo sapiens | 1-palmitoyl-glycerophosphocholine + oleic acid | - |
? | |
| diarachidonylphosphatidylcholine + H2O | - |
Homo sapiens | arachidonylphosphatidylcholine + arachidonic acid | - |
? | |
| phosphatidylcholine + H2O | - |
Homo sapiens | 1-acylglycerophosphocholine + fatty acid | - |
? | |
| phosphatidylethanolamine + H2O | - |
Homo sapiens | 1-acylglycerophosphorylethanolamine + fatty acid | - |
? | |
| phosphatidylglycerol + H2O | - |
Homo sapiens | 1-acylglycerol + fatty acid | - |
? | |
| phospholipids + H2O | - |
Homo sapiens | ? | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | 8.5 | substrate: egg yolk emulsion | Homo sapiens |
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