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Literature summary for 3.1.1.4 extracted from

  • Donne-Op den Kelder, G.M.; de Haas, G.H.; Egmond, M.R.
    Localization of the second calcium ion binding site in porcine and equine phospholipase A2 (1983), Biochemistry, 22, 2470-2478.
    View publication on PubMed
Search for more literature for 3.1.1.4

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ two Ca2+ binding sites, first Ca2+ is strongly bound and essential for enzyme activity, the second binds more weakly and improves the enzymes affinity for lipid-water interfaces Homo sapiens
Ca2+ two Ca2+ binding sites, first Ca2+ is strongly bound and essential for enzyme activity, the second binds more weakly and improves the enzymes affinity for lipid-water interfaces Sus scrofa
Ca2+ two Ca2+ binding sites, first Ca2+ is strongly bound and essential for enzyme activity, the second binds more weakly and improves the enzymes affinity for lipid-water interfaces Bos taurus
Ca2+ two Ca2+ binding sites, first Ca2+ is strongly bound and essential for enzyme activity, the second binds more weakly and improves the enzymes affinity for lipid-water interfaces Equus caballus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
13750
-
 amino acid composition analysis Bos taurus
13900
-
 amino acid composition analysis Homo sapiens
13900
-
 amino acid composition analysis Equus caballus
13950
-
 amino acid composition analysis Sus scrofa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
phospholipids + H2O Homo sapiens
-
 ?
-
 ?
phospholipids + H2O Sus scrofa
-
 ?
-
 ?
phospholipids + H2O Bos taurus
-
 ?
-
 ?
phospholipids + H2O Equus caballus
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Equus caballus
-
-
-
Homo sapiens
-
-
-
Sus scrofa
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens
-
 Sus scrofa
-
 Bos taurus
-
 Equus caballus

Source Tissue

Source Tissue Comment Organism Textmining
pancreas
-
 Homo sapiens
-
pancreas
-
 Sus scrofa
-
pancreas
-
 Bos taurus
-
pancreas
-
 Equus caballus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
573
-
 pH 8, micellar 1,2-dioctanoyl-sn-glycero-3-phosphocholine, 0.013 mM Ca2+ Homo sapiens
1648
-
 pH6, micellar 1,2-dioctanoyl-sn-glycero-3-phosphocholine, isoenzyme of e-amidinated PLA, 0.71 mM Ca2+ Sus scrofa
1693
-
 pH6, micellar 1,2-dioctanoyl-sn-glycero-3-phosphocholine, 0.42 mM Ca2+ Homo sapiens
2038
-
 pH6, micellar 1,2-dioctanoyl-sn-glycero-3-phosphocholine, 0.64 mM Ca2+ Sus scrofa
2170
-
 pH8, micellar 1,2-dioctanoyl-sn-glycero-3-phosphocholine, iso-AMPA, 0.30 mM Ca2+ Sus scrofa
2725
-
 pH8, micellar 1,2-dioctanoyl-sn-glycero-3-phosphocholine, 2.0 mM Ca2+ Bos taurus
2910
-
 pH6, micellar 1,2-dioctanoyl-sn-glycero-3-phosphocholine, 8.1 mM Ca2+ Bos taurus
6671
-
 pH6, micellar 1,2-dioctanoyl-sn-glycero-3-phosphocholine, 0.79 mM Ca2+ Equus caballus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O
-
 Homo sapiens 1-octanoyl-sn-glycero-3-phosphocholine + octanoate
-
 ?
1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O
-
 Sus scrofa 1-octanoyl-sn-glycero-3-phosphocholine + octanoate
-
 ?
1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O
-
 Bos taurus 1-octanoyl-sn-glycero-3-phosphocholine + octanoate
-
 ?
1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O
-
 Equus caballus 1-octanoyl-sn-glycero-3-phosphocholine + octanoate
-
 ?
phospholipids + H2O
-
 Homo sapiens ?
-
 ?
phospholipids + H2O
-
 Sus scrofa ?
-
 ?
phospholipids + H2O
-
 Bos taurus ?
-
 ?
phospholipids + H2O
-
 Equus caballus ?
-
 ?