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Literature summary for 3.1.1.37 extracted from
- Preparation and properties of a steroid lactonase (1965), Arch. Biochem. Biophys., 109, 29-35.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| HgCl2 | - |
Acremonium chrysogenum |  |
| p-chloromercuriphenylsulfonate | - |
Acremonium chrysogenum | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | optimum: 0.1 M, enhances | Acremonium chrysogenum | |
| Mn2+ | optimum: 0.1 M, enhances | Acremonium chrysogenum | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| testololactone + H2O | Acremonium chrysogenum | - |
? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Acremonium chrysogenum | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Acremonium chrysogenum |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 16alpha-hydroxytestololactone + H2O | 50% the rate of testololactone | Acremonium chrysogenum | 16alpha-hydroxytestolate | - |
? | |
| additional information | not: steroids containing gamma-lactones, digitoxigenin, spirolactone | Acremonium chrysogenum | ? | - |
? | |
| testolate | lactone formation more rapidly than lactone hydrolysis, only at pH 6, presence of Mn2+ | Acremonium chrysogenum | testololactone + H2O | - |
r | |
| testololactone + H2O | - |
Acremonium chrysogenum | testolate | - |
r | |
| testololactone + H2O | - |
Acremonium chrysogenum | ? | - |
? | |
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