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Literature summary for 3.1.1.34 extracted from
- Mutation of tryptophan residues in lipoprotein lipase. Effects on stability, immunoreactivity, and catalytic properties (1997), J. Biol. Chem., 272, 766-772.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Bos taurus |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| W114A | completely inactive lipase | Bos taurus |
| W390A | decreased activity with monoclonal antibody 5D2, decreased activity against a synthetic emulsion of long-chain triacylglycerols and in particular against rat lymph chylomicrons | Bos taurus |
| W55A | completely inactive lipase | Bos taurus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
wild-type enzyme and mutant enzymes W382A, W390A, W393A, W394A, W393A/W394A and W114A | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| milk | - |
Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| chylomicrons + H2O | wild-type enzyme and mutant enzymes | Bos taurus | ? | - |
? |  |
| tributyrin + H2O | wild-type enzyme and mutant enzymes | Bos taurus | ? | - |
? | |
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Release 2023.1 (January 2023)
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