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Literature summary for 3.1.1.34 extracted from

  • Davies, P.J.; Berry, S.A.; Shipley, G.L.; Eckel, R.H.; Hennuyer, N.; Crombie, D.L.; Ogilvie, K.M.; Peinado-Onsurbe, J.; Fievet, C.; Leibowitz, M.D.; Heyman, R.A.; Auwerx, J.
    Metabolic effects of rexinoids: tissue-specific regulation of lipoprotein lipase activity (2001), Mol. Pharmacol., 59, 170-176.
    View publication on PubMed
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Inhibitors

Inhibitors Comment Organism Structure
LG268 retinoid X receptor selective retinoid, almost complete inactivation of LPL activity in heart muscle after administration of 30 mg/kg/d, approx. 50% inhibition in skeletal muscle Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
triacylglycerol + H2O Rattus norvegicus
-
 diacylglycerol + a carboxylate
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cardiac muscle
-
 Rattus norvegicus
-
skeletal muscle
-
 Rattus norvegicus
-
white adipose tissue
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
triacylglycerol + H2O
-
 Rattus norvegicus diacylglycerol + a carboxylate
-
 ?

Synonyms

Synonyms Comment Organism
LPL
-
 Rattus norvegicus