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Literature summary for 3.1.1.28 extracted from
- Carnitine ester hydrolase of rat liver (1969), J. Biol. Chem., 244, 4448-4453.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | - |
Rattus norvegicus |  |
| Cu2+ | - |
Rattus norvegicus | |
| Decanoyl D-carnitine | - |
Rattus norvegicus | |
| NaF | - |
Rattus norvegicus | |
| sodium cholate | - |
Rattus norvegicus | |
| sulfhydryl reagents | - |
Rattus norvegicus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 3.2 | - |
Decanoyl-L-carnitine | - |
Rattus norvegicus | |
| 5 | - |
palmitoyl-L-carnitine | - |
Rattus norvegicus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Rattus norvegicus | - |
- |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| kidney | - |
Rattus norvegicus | - |
| liver | - |
Rattus norvegicus | - |
| pancreas | - |
Rattus norvegicus | - |
| small intestine | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| decanoyl-L-carnitine + H2O | - |
Rattus norvegicus | decanoate + L-carnitine | - |
? | |
| glycerol monopalmitate + H2O | slight | Rattus norvegicus | glycerol + palmitic acid | - |
? | |
| additional information | acts on higher fatty acid, C6-C18 esters of L-carnitine, highest activity with O-decanoyl-L-carnitine | Rattus norvegicus | ? | - |
? | |
| additional information | not: D-carnitine esters, palmitoyl CoA | Rattus norvegicus | ? | - |
? | |
| additional information | not: p-nitrophenyl palmitate, glycerol tripalmitate, cholesterol palmitate | Rattus norvegicus | ? | - |
? | |
| palmitoyl-L-carnitine + H2O | - |
Rattus norvegicus | palmitic acid + L-carnitine | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
- |
Rattus norvegicus |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 6 | 9 | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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