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Literature summary for 3.1.1.23 extracted from
- Purification and characterization of rat liver microsomal monoacylglycerol lipase in comparison to the other esterases (1977), Biochim. Biophys. Acta, 488, 128-139.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| diisopropyl fluorophosphate | - |
Rattus norvegicus |  |
| NaF | - |
Rattus norvegicus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.12 | - |
1-monomyristoylglycerol | - |
Rattus norvegicus | |
| 0.2 | - |
2-monomyristoylglycerol | - |
Rattus norvegicus | |
| 0.49 | - |
sn-2-monooleoylglycerol | - |
Rattus norvegicus | |
| 0.51 | - |
1-monooleoylglycerol | - |
Rattus norvegicus | |
| 40 | - |
Tributyrylglycerol | - |
Rattus norvegicus | |
| 200 | - |
methyl butyrate | - |
Rattus norvegicus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Rattus norvegicus | - |
- |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 62000 | - |
1 * 62000, SDS-PAGE | Rattus norvegicus |
| 63000 | - |
gel filtration | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Rattus norvegicus |
Storage Stability
| Storage Stability | Organism |
|---|---|
| 0°C, stable for 2 weeks | Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1-monomyristoylglycerol + H2O | - |
Rattus norvegicus | myristic acid + glycerol | - |
? | |
| 1-monopalmitoylglycerol + H2O | - |
Rattus norvegicus | palmitic acid + glycerol | - |
? | |
| 2-monomyristoylglycerol + H2O | - |
Rattus norvegicus | myristic acid + glycerol | - |
? | |
| 2-monoolein + H2O | - |
Rattus norvegicus | ? | - |
? | |
| 2-monopalmitoylglycerol + H2O | - |
Rattus norvegicus | palmitic acid + glycerol | - |
? | |
| methyl butyrate + H2O | - |
Rattus norvegicus | methanol + butanoate | - |
? | |
| tributyrylglycerol + H2O | - |
Rattus norvegicus | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 62000, SDS-PAGE | Rattus norvegicus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.5 | - |
- |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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