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Literature summary for 3.1.1.23 extracted from
- Monoacylglycerol lipase from rat adipose tissue (1981), Methods Enzymol., 71, 647-652.
No PubMed abstract available
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| diisopropyl fluorophosphate | - |
Rattus norvegicus |  |
| HgCl2 | HgCl2 | Rattus norvegicus | |
| PCMB | - |
Rattus norvegicus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 32900 | - |
x * 32900, SDS-PAGE | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| adipose tissue | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 350 | - |
- |
Rattus norvegicus |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -70°C, 20 mM Tris-HCl or phosphate buffer, pH 7.0, 1 mM dithiothreitol, 1 mM EDTA, 0.2% C13E12, stable for several months | Rattus norvegicus |
| 4°C, 20 mM Tris-HCl or phosphate buffer, pH 7.0, 1 mM dithiothreitol, 1 mM EDTA, 0.2% C13E12, half-life: 9 days | Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1(3)-monooleoylglycerol + H2O | - |
Rattus norvegicus | oleic acid + glycerol | - |
? | |
| 2-monooleoylglycerol + H2O | - |
Rattus norvegicus | oleic acid + glycerol | - |
? | |
| monooleoylglycerol + H2O | - |
Rattus norvegicus | oleic acid + glycerol | - |
? | |
| additional information | no activity against long-chain diacylglycerols and triacylglycerols, cholesterol ester, or lysophosphatidylcholine | Rattus norvegicus | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 32900, SDS-PAGE | Rattus norvegicus |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 4 | - |
half-life: 9 days | Rattus norvegicus |
| 21 | - |
half-life: 36 h | Rattus norvegicus |
| 37 | - |
half-life: 9 h | Rattus norvegicus |
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Release 2023.1 (January 2023)
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