Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.1.2 extracted from

  • Olama, S.M.; Elarman, M.M.
    Evaluation of paraoxonase and arylesterase activities in Egyptian patients with ankylosing spondylitis (2013), Rheumatol. Int., 33, 1487-1494.
    View publication on PubMed

Application

Application Comment Organism
medicine in patients with ankylosing spondylitis with active disease, levels of serum triglycerides, total cholesterol, low denstiy lipoprotein and malondialdehyde are significantly elevated while high density liporpoteon, paraoxonase PON1 and arylesterase ARE levels are lower than those with no active ankylosing spondylitis. Decrease in the PON1/ARE activity leading to generation of oxidative stress may play an important role in the pathogenesis of ankylosing spondylitis. Activity of PON1/ARE in patients with ankylosing spondylitis seems to be strictly correlated with the activity of the inflammatory process Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
serum
-
Homo sapiens
-