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Literature summary for 3.1.1.2 extracted from

  • Kasprzak, M.; Iskra, M.; Majewski, W.; Wielkoszynski, T.
    Arylesterase and paraoxonase activity of paraoxonase (PON1) affected by ischemia in the plasma of patients with arterial occlusion of the lower limbs (2009), Clin. Biochem., 42, 50-56.
    View publication on PubMed
Search for more literature for 3.1.1.2

Application

Application Comment Organism
medicine the arylesterase activity of PON1 is affected by critical ischemia of the lower limbs Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
additional information the arylesterase activity of PON1 is not correlated with plasma concentrations of total cholesterol, low density lipoprotein-cholesterol, high density lipoprotein-cholesterol, or triacylglycerol in atherosclerosis obliterans patients Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ dependent on Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P27169
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
 Homo sapiens
-
liver the enzyme is synthesized in the liver Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information PON1 contains paraoxonase and arylesterase activities Homo sapiens ?
-
 ?
phenyl acetate + H2O arylesterase activity is independent of the polymorphic form of PON1 Homo sapiens phenol + acetate
-
 ?