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Literature summary for 3.1.1.19 extracted from
- Aldono- and uronolactonases of animal tissues (1958), J. Biol. Chem., 233, 794-799.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| EDTA | - |
Rattus norvegicus |  |
| p-chloromercuribenzoate | - |
Rattus norvegicus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 8 | - |
D-glucurono-6,2-lactone | - |
Rattus norvegicus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Rattus norvegicus | - |
- |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Co2+ | reactivation after treatment with EDTA | Rattus norvegicus | |
| Fe2+ | reactivation after treatment with EDTA | Rattus norvegicus | |
| Mg2+ | reactivation after treatment with EDTA | Rattus norvegicus | |
| Mn2+ | reactivation after treatment with EDTA | Rattus norvegicus | |
| Zn2+ | reactivation after treatment with EDTA | Rattus norvegicus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
| Canis lupus familiaris | - |
- |
- |
| Cavia porcellus | - |
- |
- |
| Oryctolagus cuniculus | - |
- |
- |
| Platyrrhini | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
| Sus scrofa | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-glucurono-6,2-lactone + H2O | - |
Cavia porcellus | D-glucuronic acid | - |
? | |
| D-glucurono-6,2-lactone + H2O | - |
Rattus norvegicus | D-glucuronic acid | - |
? | |
| D-glucurono-6,2-lactone + H2O | - |
Sus scrofa | D-glucuronic acid | - |
? | |
| D-glucurono-6,2-lactone + H2O | - |
Bos taurus | D-glucuronic acid | - |
? | |
| D-glucurono-6,2-lactone + H2O | - |
Oryctolagus cuniculus | D-glucuronic acid | - |
? | |
| D-glucurono-6,2-lactone + H2O | - |
Canis lupus familiaris | D-glucuronic acid | - |
? | |
| D-glucurono-6,2-lactone + H2O | - |
Platyrrhini | D-glucuronic acid | - |
? | |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
- |
- |
86% loss of activity after 3 d | Rattus norvegicus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | 8 | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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