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Literature summary for 3.1.1.17 extracted from

  • Tavori, H.; Khatib, S.; Aviram, M.; Vaya, J.
    Characterization of the PON1 active site using modeling simulation, in relation to PON1 lactonase activity (2008), Bioorg. Med. Chem., 16, 7504-7509.
    View publication on PubMed
Search for more literature for 3.1.1.17

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(1R,5S)-oxabicyclooctenone + H2O hydrolysis: 0.83 micromol/min/mg Homo sapiens ?
-
 ?
(1S,5R)-oxabicyclooctenone + H2O hydrolysis: 1.67 micromol/min/mg Homo sapiens ?
-
 ?
alpha-angelica lactone + H2O hydrolysis: 18.3 micromol/min/mg Homo sapiens ?
-
 ?
beta-hydroxybutyrolactone + H2O hydrolysis: 3.83 micromol/min/mg Homo sapiens ?
-
 ?
delta-decanolactone + H2O hydrolysis: 25.1 micromol/min/mg Homo sapiens ?
-
 ?
delta-dodecanolactone + H2O hydrolysis: 9.65 micromol/min/mg Homo sapiens ?
-
 ?
delta-hexalactone + H2O hydrolysis: 7.2 micromol/min/mg Homo sapiens ?
-
 ?
delta-nonalactone + H2O hydrolysis: 15 micromol/min/mg Homo sapiens 5-hydroxynonanoate
-
 ?
delta-undecatiolactone + H2O hydrolysis: 28.7 micromol/min/mg Homo sapiens ?
-
 ?
delta-valerolactone + H2O hydrolysis: 67.1 micromol/min/mg Homo sapiens ?
-
 ?
dihydrocoumarin + H2O hydrolysis: 12.99 micromol/min/mg Homo sapiens ?
-
 ?
epsilon-caprolactone + H2O hydrolysis: 14.8 micromol/min/mg Homo sapiens ?
-
 ?
gamma-butyrolactone + H2O hydrolysis: 3.21 micromol/min/mg Homo sapiens ?
-
 ?
gamma-decalactone + H2O hydrolysis: 17.38 micromol/min/mg Homo sapiens ?
-
 ?
gamma-heptalactone + H2O hydrolysis: 5.72 micromol/min/mg Homo sapiens ?
-
 ?
gamma-hexalactone + H2O hydrolysis: 5.17 micromol/min/mg Homo sapiens ?
-
 ?
gamma-nonalactone + H2O hydrolysis: 14.47 micromol/min/mg Homo sapiens 4-hydroxynonanoate
-
 ?
gamma-octalactone + H2O hydrolysis: 6.92 micromol/min/mg Homo sapiens ?
-
 ?
gamma-undecalactone + H2O hydrolysis: 12.72 micromol/min/mg Homo sapiens ?
-
 ?
gamma-valerolactone + H2O hydrolysis: 4.5 micromol/min/mg Homo sapiens ?
-
 ?
homogenestic acid lactone + H2O hydrolysis: 32.95 micromol/min/mg Homo sapiens ?
-
 ?
additional information relating lactones rate of hydrolysis reveal an inverse correlation with the docking energy of the ligands-PON1 complex, and a direct correlation with the lactone side chain length Homo sapiens ?
-
 ?
phenyl acetate + H2O hydrolysis: 112 micromol/min/mg Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
paraoxonase1
-
 Homo sapiens
PON1
-
 Homo sapiens