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Literature summary for 3.1.1.13 extracted from

  • Sekiya, M.; Osuga, J.; Igarashi, M.; Okazaki, H.; Ishibashi, S.
    The role of neutral cholesterol ester hydrolysis in macrophage foam cells (2011), J. Artheroscler. Thromb., 18, 359-364.
    View publication on PubMed
Search for more literature for 3.1.1.13

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
 Mus musculus 5783
-
endoplasmic reticulum
-
 Homo sapiens 5783
-
membrane transmembrane protein Mus musculus 16020
-
membrane transmembrane protein Homo sapiens 16020
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
45700
-
 x * 45700, calculated from amino acid sequence Mus musculus

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein
-
 Mus musculus
glycoprotein
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
adrenal gland
-
 Mus musculus
-
brain
-
 Mus musculus
-
foam cell
-
 Mus musculus
-
foam cell
-
 Homo sapiens
-
heart
-
 Mus musculus
-
kidney most abundant expression in kidney Mus musculus
-
liver
-
 Mus musculus
-
macrophage highly expressed in macrophages Mus musculus
-
macrophage highly expressed in macrophages Homo sapiens
-

Subunits

Subunits Comment Organism
? x * 45700, calculated from amino acid sequence Mus musculus

Synonyms

Synonyms Comment Organism
KIAA1263/AADACL1
-
 Mus musculus
KIAA1263/AADACL1
-
 Homo sapiens
NCEH
-
 Mus musculus
NCEH
-
 Homo sapiens
Nceh1
-
 Mus musculus
Nceh1
-
 Homo sapiens
neutral cholesterol ester hydrolase 1
-
 Mus musculus
neutral cholesterol ester hydrolase 1
-
 Homo sapiens

Expression

Organism Comment Expression
Mus musculus NCEH1 becomes up-regulated during macrophage differentiation up
Homo sapiens NCEH1 becomes up-regulated during macrophage differentiation up

General Information

General Information Comment Organism
malfunction neutral cholesterol ester hydrolase 1/hormone-sensitive lipase-deficient mice develop atherosclerosis faster than the control and single deficient bone marrow recipients Mus musculus
physiological function neutral cholesterol ester hydrolase 1 protects against foam cell formation and atherosclerosis Mus musculus
physiological function neutral cholesterol ester hydrolase 1 protects against foam cell formation and atherosclerosis Homo sapiens