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Literature summary for 3.1.1.13 extracted from

  • Chiou, S.Y.; Lai, C.Y.; Lin, L.Y.; Lin, G.
    Probing stereoselective inhibition of the acyl binding site of cholesterol esterase with four diastereomers of 2'-N-alpha-methylbenzylcarbamyl-1, 1'-bi-2-naphthol (2005), BMC Biochem., 6, 17.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.1.13

Inhibitors

Inhibitors Comment Organism Structure
(1R, alphaR)-2'-N-alpha-methylbenzylcarbamyl-1,1'-bi-2-naphthol
-
 Bos taurus
(1R, alphaS)-2'-N-alpha-methylbenzylcarbamyl-1,1'-bi-2-naphthol
-
 Bos taurus
(1S, alphaR)-2'-N-alpha-methylbenzylcarbamyl-1,1'-bi-2-naphthol
-
 Bos taurus
(1S, alphaS)-2'-N-alpha-methylbenzylcarbamyl-1,1'-bi-2-naphthol
-
 Bos taurus
(R)-2'-N-butylcarbamyl-1,1'-bi-naphthol
-
 Bos taurus
(S)-2'-N-butylcarbamyl-1,1'-bi-naphthol
-
 Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
p-nitrophenyl butyrate + H2O
-
 Bos taurus p-nitrophenol + butyrate
-
 ?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.0002
-
 (1R, alphaR)-2'-N-alpha-methylbenzylcarbamyl-1,1'-bi-2-naphthol pH 7.0, 25°C Bos taurus
0.0005
-
 (1R, alphaS)-2'-N-alpha-methylbenzylcarbamyl-1,1'-bi-2-naphthol pH 7.0, 25°C Bos taurus
0.0008
-
 (R)-2'-N-butylcarbamyl-1,1'-bi-naphthol pH 7.0, 25°C Bos taurus
0.0013
-
 (S)-2'-N-butylcarbamyl-1,1'-bi-naphthol pH 7.0, 25°C Bos taurus
0.002
-
 (1S, alphaR)-2'-N-alpha-methylbenzylcarbamyl-1,1'-bi-2-naphthol pH 7.0, 25°C Bos taurus
0.006
-
 (1S, alphaS)-2'-N-alpha-methylbenzylcarbamyl-1,1'-bi-2-naphthol pH 7.0, 25°C Bos taurus