Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-nitrophenyl-N-allyl carbamate | mechanism of inhibition by these pseudo-substrate inhibitors, via a 2-step reaction including the formation of a tetrahedral enzyme-inhibitor adduct and the formation of the carbamyl-enzyme, inhibition kinetics | Sus scrofa | |
4-nitrophenyl-N-butyl carbamate | mechanism of inhibition by these pseudo-substrate inhibitors, via a 2-step reaction including the formation of a tetrahedral enzyme-inhibitor adduct and the formation of the carbamyl-enzyme, inhibition kinetics | Sus scrofa | |
4-nitrophenyl-N-chloroethyl carbamate | mechanism of inhibition by these pseudo-substrate inhibitors, via a 2-step reaction including the formation of a tetrahedral enzyme-inhibitor adduct and the formation of the carbamyl-enzyme, inhibition kinetics | Sus scrofa | |
4-nitrophenyl-N-hexyl carbamate | mechanism of inhibition by these pseudo-substrate inhibitors, via a 2-step reaction including the formation of a tetrahedral enzyme-inhibitor adduct and the formation of the carbamyl-enzyme, inhibition kinetics | Sus scrofa | |
4-nitrophenyl-N-methylphenyl carbamate | mechanism of inhibition by these pseudo-substrate inhibitors, via a 2-step reaction including the formation of a tetrahedral enzyme-inhibitor adduct and the formation of the carbamyl-enzyme, inhibition kinetics | Sus scrofa | |
4-nitrophenyl-N-octyl carbamate | mechanism of inhibition by these pseudo-substrate inhibitors, via a 2-step reaction including the formation of a tetrahedral enzyme-inhibitor adduct and the formation of the carbamyl-enzyme, inhibition kinetics | Sus scrofa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | kinetics | Sus scrofa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
steryl ester + H2O = sterol + fatty acid | a group of enzymes of broad specificity, acting on esters of sterols and long-chain fatty acids, that may also bring about the esterification of sterols. Activated by bile salts, reaction mechanism, catalytic triad consists of Ser194, His435, and Asp320 | Sus scrofa |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
pancreas | - |
Sus scrofa | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-nitrophenyl butyrate + H2O | - |
Sus scrofa | 4-nitrophenol + butyrate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
bile salt-activated lipase | - |
Sus scrofa |
CEase | - |
Sus scrofa |
cholesterol esterase | - |
Sus scrofa |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0026 | - |
4-nitrophenyl-N-butyl carbamate | pH 7.0, 25°C, pre-steady-state kinetic | Sus scrofa | |
0.0032 | - |
4-nitrophenyl-N-hexyl carbamate | pH 7.0, 25°C, pre-steady-state kinetic | Sus scrofa | |
0.0036 | - |
4-nitrophenyl-N-octyl carbamate | pH 7.0, 25°C, pre-steady-state kinetic | Sus scrofa | |
0.0038 | - |
4-nitrophenyl-N-allyl carbamate | pH 7.0, 25°C, pre-steady-state kinetic | Sus scrofa | |
0.0044 | - |
4-nitrophenyl-N-methylphenyl carbamate | pH 7.0, 25°C, pre-steady-state kinetic | Sus scrofa | |
0.0058 | - |
4-nitrophenyl-N-chloroethyl carbamate | pH 7.0, 25°C, pre-steady-state kinetic | Sus scrofa |