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Literature summary for 3.1.1.13 extracted from

  • Feaster, S.R.; Quinn, D.M.
    Mechanism-based inhibitors of mammalian cholesterol esterase (1997), Methods Enzymol., 286, 231-252.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
Trihydroxy bile salts
-
Sus scrofa
Trihydroxy bile salts
-
Rattus sp.

Inhibitors

Inhibitors Comment Organism Structure
2-(5,6,7,8)-tetrahydronaphthyl-N-hexyl carbamate biphasic inhibition time-course Rattus sp.
haloketones
-
Sus scrofa
hexylboronic acids
-
Sus scrofa
phenyl-n-butylboronic acid tight-binding competetive inhibitor Sus scrofa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
cholesteryl esters + H2O Sus scrofa important role in fat digestion in infants cholesterol + fatty acid
-
r
cholesteryl esters + H2O Rattus sp. important role in fat digestion in infants cholesterol + fatty acid
-
r

Organism

Organism UniProt Comment Textmining
Rattus sp.
-
-
-
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
pancreas
-
Sus scrofa
-
pancreas
-
Rattus sp.
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cholesteryl esters + H2O important role in fat digestion in infants Sus scrofa cholesterol + fatty acid
-
r
cholesteryl esters + H2O important role in fat digestion in infants Rattus sp. cholesterol + fatty acid
-
r
p-nitrophenyl butyrate + H2O
-
Sus scrofa p-nitrophenol + butanoic acid
-
r
p-nitrophenyl butyrate + H2O
-
Rattus sp. p-nitrophenol + butanoic acid
-
?

Synonyms

Synonyms Comment Organism
CEase
-
Sus scrofa
CEase
-
Rattus sp.