Cloned (Comment) | Organism |
---|---|
gene At3g10870 or AtMES17, phylogenetic analysis | Arabidopsis thaliana |
Protein Variants | Comment | Organism |
---|---|---|
additional information | incubating seedlings in the presence of indole-3-acetic acid methyl ester show that mes17 mutants hydrolyze only 40% of the indole-3-acetic acid methyl ester taken up by plants, whereas wild-type plants hydrolyze 100% of absorbed. Roots of Arabidopsis plants overexpressing AtMES17 show increased sensitivity to indole-3-acetic acid methyl ester but not to indole-3-acetic acid. Additionally, mes17 plants have longer hypocotyls and display increased expression of the auxin-responsive DR5:beta-glucuronidase reporter gene, suggesting a perturbation in indole-3-acetic acid homeostasis and/or transport | Arabidopsis thaliana |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
methyl 1H-indole-3-carboxylate + H2O | Arabidopsis thaliana | - |
methanol + 1H-indole-3-carboxylate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | Q9SG92 | gene At3g10870 or AtMES17 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
additional information | AtMES17 is expressed at the highest levels in shoot apex, stem, and root, expression pattern of AtMES17, overview | Arabidopsis thaliana | - |
root | - |
Arabidopsis thaliana | - |
seedling | - |
Arabidopsis thaliana | - |
shoot | apex | Arabidopsis thaliana | - |
stem | - |
Arabidopsis thaliana | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
methyl 1H-indole-3-carboxylate + H2O | - |
Arabidopsis thaliana | methanol + 1H-indole-3-carboxylate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MeIAA esterase | - |
Arabidopsis thaliana |
More | the enzyme belongs to the methyl esterase family | Arabidopsis thaliana |
General Information | Comment | Organism |
---|---|---|
malfunction | methyl 1H-indole-3-carboxylate exerts inhibitory activity on the growth of wild-type roots when applied exogenously. However, the roots of Arabidopsis plants carrying T-DNA insertions in the putative MeIAA esterase gene AtMES17 displays significantly decreased sensitivity to indole-3-acetic acid methyl ester compared with wild-type roots while remaining as sensitive to free indole.3.acetic acid as wild-type roots | Arabidopsis thaliana |
physiological function | indole-3-acetic acid methyl ester, i.e. methyl 1H-indole-3-carboxylate, is an inactive form of indole-3-acetic acid, and the manifestations of indole-3-acetic acid methyl ester in vivo activity are due to the action of free indole-3-acetic acid that is generated from indole-3-acetic acid methyl ester upon hydrolysis by one or more plant esterases | Arabidopsis thaliana |