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Literature summary for 3.1.1.1 extracted from

  • Zhu, Q.G.; Hu, J.H.; Liu, J.Y.; Lu, S.W.; Liu, Y.X.; Wang, J.
    Stereoselective characteristics and mechanisms of epidermal carboxylesterase metabolism observed in HaCaT keratinocytes (2007), Biol. Pharm. Bull., 30, 532-536.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
2-chloro-3,4-dimethoxybenzil
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HaCaT cell keratinocyte, high abundance of isoform hCE2, but not hCE1 Homo sapiens
-
L-02 cell hepatocyte, high abundance of isoforms hCE1 and hCE2 Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ketoprofen ethyl ester + H2O
-
Homo sapiens R-ketoprofen + ethanol R-isomer is main product of keratinocyte enzyme ?