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Literature summary for 3.1.1.1 extracted from

  • Mori, M.; Hosokawa, M.; Ogasawara, Y.; Tsukada, E.; Chiba, K.
    cDNA cloning, characterization and stable expression of a novel human brain carboxylesterase (1999), FEBS Lett., 458, 17-22.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
-
Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0229
-
4-nitrophenyl acetate isoenzyme hBr3/pTARGET Homo sapiens
0.365
-
4-nitrophenyl acetate isoenzyme HU1/pTARGET Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the enzyme may function as a blood-brain barrier to protect the central nervous system from ester or amide compounds ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens P23141 isoenzyme hBr3/pTARGET and HU1/pTARGET
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-nitrophenyl acetate + H2O
-
Homo sapiens 4-nitrophenol + acetate
-
?
additional information the enzyme may function as a blood-brain barrier to protect the central nervous system from ester or amide compounds Homo sapiens ?
-
?
oleoyl-CoA + H2O
-
Homo sapiens oleic acid + CoA
-
?
palmitoyl-CoA + H2O weak Homo sapiens palmitic acid + CoA
-
?
temocapril + H2O weak Homo sapiens ?
-
?