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Literature summary for 3.1.1.1 extracted from
- Kinetic properties of human pancreatic carboxylesterase (1983), Biochim. Biophys. Acta, 754, 142-149.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| taurocholate | activates | Homo sapiens |  |
| taurocholate | non-essential activator | Homo sapiens | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 1.3 | - |
4-nitrophenyl acetate | enzyme from human milk | Homo sapiens | |
| 1.3 | - |
cholesterol oleate | enzyme from human pancreas | Homo sapiens | |
| 1.5 | - |
4-nitrophenyl acetate | enzyme from human pancreas | Homo sapiens | |
| 2 | - |
cholesterol oleate | enzyme from human milk | Homo sapiens | |
| 3.9 | - |
triolein | enzyme from human pancreas | Homo sapiens | |
| 8.3 | - |
triolein | enzyme from human milk | Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| a carboxylic ester + H2O = an alcohol + a carboxylate | rapid-equilibrium random mechanism | Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| milk | - |
Homo sapiens | - |
| pancreas | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-nitrophenyl acetate + H2O | - |
Homo sapiens | 4-nitrophenol + acetate | - |
? | |
| cholesterol oleate + H2O | - |
Homo sapiens | cholesterol + oleate | - |
? | |
| triolein + H2O | - |
Homo sapiens | ? | - |
? | |
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