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Literature summary for 2.9.1.2 extracted from

  • Manhas, R.; Gowri, V.S.; Madhubala, R.
    Leishmania donovani encodes a functional selenocysteinyl-tRNA synthase (2016), J. Biol. Chem., 291, 1203-1220.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.9.1.2

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli SelA-deficient strain JS1 Leishmania donovani

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Leishmania donovani 5737
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
O-phospho-L-seryl-tRNASec + selenophosphate + H2O Leishmania donovani
-
 L-selenocysteinyl-tRNASec + phosphate
-
 ?
O-phospho-L-seryl-tRNASec + selenophosphate + H2O Leishmania donovani Bob
-
 L-selenocysteinyl-tRNASec + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Leishmania donovani
-
-
-
Leishmania donovani Bob
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
promastigote
-
 Leishmania donovani
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
O-phospho-L-seryl-tRNASec + selenophosphate + H2O
-
 Leishmania donovani L-selenocysteinyl-tRNASec + phosphate
-
 ?
O-phospho-L-seryl-tRNASec + selenophosphate + H2O
-
 Leishmania donovani Bob L-selenocysteinyl-tRNASec + phosphate
-
 ?

Subunits

Subunits Comment Organism
homotetramer
-
 Leishmania donovani

Synonyms

Synonyms Comment Organism
Selenocysteinyl-tRNA synthase
-
 Leishmania donovani
SepSecS
-
 Leishmania donovani

General Information

General Information Comment Organism
physiological function the enzyme is dispensable for the parasite survival Leishmania donovani