Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.8.4.1 extracted from

  • Gräwert, T.; Hohmann, H.P.; Kindermann, M.; Duval, S.; Bacher, A.; Fischer, M.
    Inhibition of methyl-CoM reductase from Methanobrevibacter ruminantium by 2-bromoethanesulfonate (2014), J. Agric. Food Chem., 62, 12487-12490.
    View publication on PubMed
Search for more literature for 2.8.4.1

Inhibitors

Inhibitors Comment Organism Structure
2-bromoethanesulfonate
-
 Methanobrevibacter ruminantium

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
28700
-
 x * 59800 + x * 47100 + x * 28700, SDS-PAGE Methanobrevibacter ruminantium
47100
-
 x * 59800 + x * 47100 + x * 28700, SDS-PAGE Methanobrevibacter ruminantium
59800
-
 x * 59800 + x * 47100 + x * 28700, SDS-PAGE Methanobrevibacter ruminantium

Organism

Organism UniProt Comment Textmining
Methanobrevibacter ruminantium
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.006
-
 pH and temperature not specified in the publication Methanobrevibacter ruminantium

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
methyl-CoM + CoB
-
 Methanobrevibacter ruminantium CoM-S-S-CoB + methane
-
 ?

Subunits

Subunits Comment Organism
? x * 59800 + x * 47100 + x * 28700, SDS-PAGE Methanobrevibacter ruminantium

Synonyms

Synonyms Comment Organism
methyl-CoM reductase
-
 Methanobrevibacter ruminantium

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.0004
-
 pH and temperature not specified in the publication Methanobrevibacter ruminantium 2-bromoethanesulfonate

General Information

General Information Comment Organism
metabolism the enzyme catalyzes the final step of methanogenesis in Methanobrevibacter ruminantium Methanobrevibacter ruminantium