Literature summary for 2.8.4.1 extracted from

Shima, S.; Krueger, M.; Weinert, T.; Demmer, U.; Kahnt, J.; Thauer, R.K.; Ermler, U.
Structure of a methyl-coenzyme M reductase from Black Sea mats that oxidize methane anaerobically (2012), Nature, 481, 98-101.

Search for more literature for 2.8.4.1

Crystallization (Commentary)

Crystallization (Comment)	Organism
sitting drop vapor diffusion method, using 25% (w/v) PEG 400, 0.1M Tris pH 8.5 and 0.2 M Li2SO4	uncultured archaeon

Inhibitors

Inhibitors	Comment	Organism	Structure
bromoethane sulfonate	-	uncultured archaeon

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
280000	-	gel filtration	uncultured archaeon

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
CH3-S-CoM + HS-CoB	uncultured archaeon	-	CoM-S-S-CoB + methane	-	r

Organism

Organism	UniProt	Comment	Textmining
uncultured archaeon	D1JBK2 and D1JBK3 and D1JBK4	subunits alpha, beta and gamma; consortia of microorganisms collected from a Black Sea mat (ANME-1)	-

Purification (Commentary)

Purification (Comment)	Organism
-	uncultured archaeon

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
CH3-S-CoM + HS-CoB	-	uncultured archaeon	CoM-S-S-CoB + methane	-	r

Subunits

Subunits	Comment	Organism
heterohexamer	-	uncultured archaeon

Synonyms

Synonyms	Comment	Organism
MCR	-	uncultured archaeon
methyl-coenzyme M reductase	-	uncultured archaeon

Cofactor

Cofactor	Comment	Organism	Structure
F-430	the enzyme contains the Ni porphinoid F430 as prosthetic group	uncultured archaeon

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Release 2023.1 (January 2023)