BRENDA - Enzyme Database
show all sequences of 2.8.3.9

Metabolic engineering of Clostridium tyrobutyricum for n-butanol production: effects of CoA transferase

Yu, L.; Zhao, J.; Xu, M.; Dong, J.; Varghese, S.; Yu, M.; Tang, I.; Yang, S.; Appl. Microbiol. Biotechnol. 99, 4917-4930 (2015)

Data extracted from this reference:

Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Clostridium tyrobutyricum
-
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
acetate + acetoacetyl-CoA
-
737542
Clostridium tyrobutyricum
acetyl-CoA + acetoacetate
-
-
-
r
butanoate + acetoacetyl-CoA
-
737542
Clostridium tyrobutyricum
butanoyl-CoA + acetoacetate
-
-
-
r
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
acetate + acetoacetyl-CoA
-
737542
Clostridium tyrobutyricum
acetyl-CoA + acetoacetate
-
-
-
r
butanoate + acetoacetyl-CoA
-
737542
Clostridium tyrobutyricum
butanoyl-CoA + acetoacetate
-
-
-
r
Other publictions for EC 2.8.3.9
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
737542
Yu
Metabolic engineering of Clost ...
Clostridium tyrobutyricum
Appl. Microbiol. Biotechnol.
99
4917-4930
2015
-
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
643839
Emmanuel
-
Butyrate:acetoacetyl-CoA trans ...
Bos taurus
Can. J. Anim. Sci.
63
355-360
1983
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
2
-
-
3
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
2
-
-
3
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
643838
Barker
Butyryl-CoA:acetoacetate CoA-t ...
Acetoanaerobium sticklandii, Clostridium sp., Clostridium sp. SB4
J. Biol. Chem.
253
1219-1225
1978
1
-
-
-
-
1
-
30
-
7
4
3
-
14
-
-
1
-
-
-
1
3
30
1
-
-
1
-
1
1
1
-
-
-
-
1
-
-
-
-
-
1
-
-
-
30
-
7
4
3
-
-
-
1
-
-
1
3
30
1
-
-
1
-
1
1
1
-
-
-
-
-
-
-
643836
Sramek
Escherichia coli coenzyme A-tr ...
Escherichia coli, Escherichia coli C22
Arch. Biochem. Biophys.
171
27-35
1975
-
-
-
-
-
-
2
2
-
-
3
-
-
3
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
2
1
2
-
-
3
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
643837
Sramek
Purification and properties of ...
Escherichia coli, Escherichia coli C22
Arch. Biochem. Biophys.
171
14-26
1975
-
-
-
-
-
-
3
2
2
-
5
2
-
3
-
1
1
-
-
-
2
-
17
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
3
1
2
2
-
5
2
-
-
1
1
-
-
2
-
17
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-