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Literature summary for 2.8.3.1 extracted from

  • Jung, Y.K.; Kim, T.Y.; Park, S.J.; Lee, S.Y.
    Metabolic engineering of Escherichia coli for the production of polylactic acid and its copolymers (2010), Biotechnol. Bioeng., 105, 161-171.
    View publication on PubMed

Application

Application Comment Organism
synthesis in an engineered Escherichia coli strain JLX7, the engineered enzyme mutant Pct540, coexpressed with an engineered Pseudomonas sp. MBEL 6-19 polyhydroxyalkanoate synthase 1, is able to effectively produce polylactic acid, a promising biomass-derived polymer, overview Anaerotignum propionicum

Cloned(Commentary)

Cloned (Comment) Organism
coexpression of the engineered mutant Pct540 from Clostridium propionicum in the engineered Escherichia coli strain JLX7 with engineered Pseudomonas sp. MBEL 6-19 polyhydroxyalkanoate synthase 1 mutant, i.e. PhaC1Ps6-19, production of polylactic acid, flux response analysis, overview. The engineered Escherichia coli strain exerts several knocked out genes, overview Anaerotignum propionicum

Protein Variants

Protein Variants Comment Organism
V193A the Pct540 mutant contains the V193A mutation, and four silent nucleotide exchanges of T78C, T669C, A1125G, T1158C Anaerotignum propionicum

Organism

Organism UniProt Comment Textmining
Anaerotignum propionicum
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Synonyms

Synonyms Comment Organism
PCT
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Anaerotignum propionicum
propionate CoA transferase
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Anaerotignum propionicum