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Literature summary for 2.8.2.9 extracted from

  • King, R.S.; Sharma, V.; Pedersen, L.C.; Kakuta, Y.; Negishi, M.; Duffel, M.W.
    Structure-function modeling of the interactions of N-alkyl-N-hydroxyanilines with rat hepatic aryl sulfotransferase IV (2000), Chem. Res. Toxicol., 13, 1251-1258.
    View publication on PubMed
Search for more literature for 2.8.2.9

Inhibitors

Inhibitors Comment Organism Structure
N-n-butyl-N-hydroxyaniline competitive, reversible Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.119
-
 N-hydroxy-N-methylaniline pH 7, 37°C Rattus norvegicus
0.161
-
 N-hydroxy-N-n-propylaniline pH 7, 37°C Rattus norvegicus
0.65
-
 N-ethyl-N-hydroxyaniline pH 7, 37°C Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
33500
-
 x * 33500, SDS-PAGE Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
homogeneity Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.8 1
-
 Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylylsulfate + 2-naphthol
-
 Rattus norvegicus adenosine 3',5'-bisphosphate + 2-naphthyl sulfate
-
 ?
3'-phosphoadenylylsulfate + N-ethyl-N-hydroxyaniline
-
 Rattus norvegicus adenosine 3',5'-bisphosphate + ?
-
 ?
3'-phosphoadenylylsulfate + N-hydroxy-N-methylaniline
-
 Rattus norvegicus adenosine 3',5'-bisphosphate + ?
-
 ?
3'-phosphoadenylylsulfate + N-hydroxy-N-n-propylaniline
-
 Rattus norvegicus adenosine 3',5'-bisphosphate + ?
-
 ?

Subunits

Subunits Comment Organism
? x * 33500, SDS-PAGE Rattus norvegicus

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.066
-
 N-n-butyl-N-hydroxyaniline pH 7, 37°C Rattus norvegicus