Literature summary for 2.8.2.9 extracted from

Duffel, M.W.; Jakoby, W.B.
On the mechanism of aryl sulfotransferase (1981), J. Biol. Chem., 256, 11123-11127.

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Inhibitors

Inhibitors	Comment	Organism	Structure
2-chloro-4-nitrophenol	-	Rattus norvegicus
2-Chloro-4-nitrophenyl sulfate	product inhibition	Rattus norvegicus
2-naphthol	potent product inhibitor	Rattus norvegicus
3'-phosphoadenylylsulfate	-	Rattus norvegicus
adenosine 3',5'-bisphosphate	-	Rattus norvegicus
phenol	poor inhibitor of the reverse reaction	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	male	-

Purification (Commentary)

Purification (Comment)	Organism
male	Rattus norvegicus

Reaction

Reaction	Comment	Organism	Reaction ID
3'-phosphoadenylyl sulfate + L-tyrosine methyl ester = adenosine 3',5'-bisphosphate + L-tyrosine methyl ester 4-sulfate	random rapid equilibrium bi bi kinetic mechanism	Rattus norvegicus	a

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3'-phosphoadenylylsulfate + 2-chloro-4-nitrophenol	-	Rattus norvegicus	adenosine 3',5'-bisphosphate + 2-chloro-4-nitrophenyl sulfate	-	r
3'-phosphoadenylylsulfate + L-tyrosine methyl ester	-	Rattus norvegicus	adenosine 3',5'-bisphosphate + L-tyrosine methyl ester 4-sulfate	-	?

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Release 2023.1 (January 2023)