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Literature summary for 2.8.2.8 extracted from
- N-sulfation of heparan sulfate regulates early branching events in the developing mammary gland (2012), J. Biol. Chem., 287, 42064-42070.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| mammary gland | - |
Mus musculus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| N-deacetylase/N-sulfotransferase | - |
Mus musculus |
| Ndst1 | isoform | Mus musculus |
| NDST2 | isoform | Mus musculus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | the absence of both isoforms Ndst1 and Ndst2 induces increased branching of the ductal epithelium in mammary gland. Ndst-deficient ducts display an apparent overabundance of branched ductal epithelia and cellular chimerism in the level of sulfated cell surface heparan sulfate | Mus musculus |
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Release 2023.1 (January 2023)
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