Literature summary for 2.8.2.8 extracted from

Holley, R.J.; Deligny, A.; Wei, W.; Watson, H.A.; Ninonuevo, M.R.; Dagaelv, A.; Leary, J.A.; Bigger, B.W.; Kjellen, L.; Merry, C.L.
Mucopolysaccharidosis type I, unique structure of accumulated heparan sulfate and increased N-sulfotransferase activity in mice lacking alpha-L-iduronidase (2011), J. Biol. Chem., 286, 37515-37524.

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Activating Compound

Activating Compound	Comment	Organism	Structure
heparin sulfate	excess heparin sulfate increases the N-sulfotransferase activity of heparin sulfate-modifying N-deacetylase/N-sulfotransferase	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	-	Mus musculus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3'-phosphoadenylylsulfate + N-deacetylated K5 polysaccharide	-	Mus musculus	adenosine 3',5'-bisphosphate + ?	-	?

Synonyms

Synonyms	Comment	Organism
N-deacetylase/N-sulfotransferase	-	Mus musculus
NDST	-	Mus musculus

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Release 2023.1 (January 2023)