Cloned (Comment) | Organism |
---|---|
expression in Saccharomyces cerevisiae | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine | Mus musculus | cerebral hypoplasia and craniofacial defects are detected in mice lacking heparan sulfate Ndst1 gene function. Ndst1 is a crucial regulator of mammalian forebrain and facial development. Properly modified heparan sulfate is necessary for neuronal, glia and neural crest development | adenosine 3',5'-bisphosphate + [heparan sulfate]-N-sulfoglucosamine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine | cerebral hypoplasia and craniofacial defects are detected in mice lacking heparan sulfate Ndst1 gene function. Ndst1 is a crucial regulator of mammalian forebrain and facial development. Properly modified heparan sulfate is necessary for neuronal, glia and neural crest development | Mus musculus | adenosine 3',5'-bisphosphate + [heparan sulfate]-N-sulfoglucosamine | - |
? |