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Literature summary for 2.8.2.8 extracted from

  • Kusche-Gullberg, M.; Eriksson, I.; Pikas, D.S.; Kjellen, L.
    Identification and expression in mouse of two heparan sulfate glucosaminyl N-deacetylase/N-sulfotransferase genes (1998), J. Biol. Chem., 273, 11902-11907.
    View publication on PubMed
Search for more literature for 2.8.2.8

Cloned(Commentary)

Cloned (Comment) Organism
DNA and RNA determination in hepatocytes Rattus norvegicus
DNA sequence determination and analysis, genetic structure and organization Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine Rattus norvegicus
-
 adenosine 3',5'-bisphosphate + [heparan sulfate]-N-sulfoglucosamine
-
 ?
3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine Mus musculus bifunctional enzyme initiates heparin and heparan sulfate biosynthesis adenosine 3',5'-bisphosphate + [heparan sulfate]-N-sulfoglucosamine
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus Q3UHN9 bifunctional enzyme possessing heparan sulfate N-deacetylase and N-sulfotransferase activity
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Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-
mastocytoma cell ie. MST cell Mus musculus
-
MST cell
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine
-
 Rattus norvegicus adenosine 3',5'-bisphosphate + [heparan sulfate]-N-sulfoglucosamine
-
 ?
3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine
-
 Mus musculus adenosine 3',5'-bisphosphate + [heparan sulfate]-N-sulfoglucosamine
-
 ?
3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine bifunctional enzyme initiates heparin and heparan sulfate biosynthesis Mus musculus adenosine 3',5'-bisphosphate + [heparan sulfate]-N-sulfoglucosamine
-
 ?