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Literature summary for 2.8.2.4 extracted from

  • Chai, X.; Guo, Y.; Jiang, M.; Hu, B.; Li, Z.; Fan, J.; Deng, M.; Billiar, T.R.; Kucera, H.R.; Gaikwad, N.W.; Xu, M.; Lu, P.; Yan, J.; Fu, H.; Liu, Y.; Yu, L.; Huang, M.; Zeng, S.; Xie, W.
    Oestrogen sulfotransferase ablation sensitizes mice to sepsis (2015), Nat. Commun., 6, 7979.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.8.2.4

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Mus musculus 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3'-phosphoadenylyl sulfate + estrone Mus musculus
-
 adenosine 3',5'-bisphosphate + estrone 3-sulfate
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus P49891
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Kupffer cell
-
 Mus musculus
-
liver
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylyl sulfate + estrone
-
 Mus musculus adenosine 3',5'-bisphosphate + estrone 3-sulfate
-
 ?

Synonyms

Synonyms Comment Organism
EST
-
 Mus musculus
oestrogen sulfotransferase
-
 Mus musculus
SULT1E1
-
 Mus musculus

Expression

Organism Comment Expression
Mus musculus lipopolysaccharide, lipopeptide Pam3CSK4, or TLR2 induce the expression of estrogen sulfotransferase up

General Information

General Information Comment Organism
malfunction enzyme ablation sensitizes mice to sepsis-induced death Mus musculus
physiological function transgenic overexpression of the enzyme promotes estrogen deactivation and sensitizes mice to cecal ligation and puncture-induced inflammatory response Mus musculus