Literature summary for 2.8.2.4 extracted from

Guo, Y.; Hu, B.; Huang, H.; Tsung, A.; Gaikwad, N.W.; Xu, M.; Jiang, M.; Ren, S.; Fan, J.; Billiar, T.R.; Huang, M.; Xie, W.
Estrogen sulfotransferase is an oxidative stress-responsive gene that gender-specifically affects liver ischemia/reperfusion injury (2015), J. Biol. Chem., 290, 14754-14764.

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Application

Application	Comment	Organism
medicine	inhibition of estrogen sulfotransferase, at least in females, represents an effective approach to manage hepatic ischemia and reperfusion injury	Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
3'-phosphoadenylyl sulfate + estrone	Mus musculus	-	adenosine 3',5'-bisphosphate + estrone 3-sulfate	-	?

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	P49891	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Mus musculus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3'-phosphoadenylyl sulfate + estrone	-	Mus musculus	adenosine 3',5'-bisphosphate + estrone 3-sulfate	-	?

Synonyms

Synonyms	Comment	Organism
EST	-	Mus musculus
estrogen sulfotransferase	-	Mus musculus

Expression

Organism	Comment	Expression
Mus musculus	liver ischemia and reperfusion induce the expression of estrogen sulfotransferase	up

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Release 2023.1 (January 2023)